Cholesterol, Diabetes, and Blood Pressure medications may help treat serious mental Illness as evidenced by a  large observational study. Investigators found individuals with schizophrenia, bipolar disorder (BPD), or nonaffective psychosis (NAP) were less likely to experience psychiatric hospitalization during periods of exposure to any of these agents compared with unexposed periods. In addition, people with schizophrenia or BPD were less likely to self-harm during exposure periods to any medications in the above-mentioned classes.  The researchers analyzed data on 142,691 patients, including 76,759 with BPD, 30,954 with schizophrenia, and 34,978 with NAP. They focused on patients prescribed statins to reduce cholesterol/heart disease, L-type calcium channel (LTCC) antagonists (such as verapamil) to treat hypertension, or biguanides (such as metformin) to treat diabetes.  Periods of exposure to statins, LTCC antagonists, and biguanides were significantly associated with reduced rates of psychiatric hospitalization in BPD, schizophrenia, and NAP.